Overview of Zopiclone

Zopiclone is a medication primarily used for short-term treatment of severe insomnia. It helps individuals fall asleep faster and prevents waking up during the night by acting on a calming neurotransmitter in the brain called gamma-aminobutyric acid (GABA). Available in both tablet form and as a liquid for those who have difficulty swallowing pills, the liquid form typically needs to be specially ordered by a doctor.

Key Information

• Onset: Zopiclone generally takes about 1 hour to start working.
• Duration of Use: It’s usually prescribed for a short period, typically 2 to 4 weeks, because the body quickly adapts to the drug, reducing its effectiveness over time. Prolonged use can also lead to dependency.
• Common Side Effects: Users may experience a metallic taste, dry mouth, or daytime drowsiness.
• Alcohol Warning: Combining Zopiclone with alcohol can lead to a dangerously deep sleep, making it difficult to wake up.
• Caution with Activities: If you feel drowsy during the day, avoid driving, riding a bike, or operating machinery.

Who Should and Should Not Take Zopiclone

Eligible Users: Most adults over 18 can take Zopiclone.

Cautionary Cases: Zopiclone may not be suitable for individuals with the following conditions:

• Allergies to Zopiclone or similar medications.
• Liver or kidney issues.
• Myasthenia gravis, a condition causing muscle weakness.
• Breathing problems, including sleep apnea.
• Mental health history.
• Previous issues with alcohol or drug misuse.
• Pregnant, trying to conceive, or breastfeeding.

Dosage and Administration

Zopiclone is available in 3.75mg and 7.5mg tablet strengths. The typical dose is a 7.5mg tablet taken just before bedtime, with effects beginning in about one hour. For those over 65 or with liver or kidney problems, a lower 3.75mg dose is often recommended to minimize the risk of side effects.

It’s crucial to take Zopiclone exactly as prescribed, and in some cases, your doctor might advise using it only a few nights a week rather than nightly.

• How to Take: Swallow the tablet whole, without crushing or chewing it. Zopiclone can be taken with or without food.
• Course Duration: Treatment usually lasts 2 to 4 weeks. Prolonged use can lead to reduced effectiveness and potential dependency. Do not abruptly stop taking zopiclone; consult your doctor for a gradual reduction in dosage to avoid withdrawal symptoms.
• Missed Dose: If you forget to take your dose by bedtime, skip it and continue with your next dose at the usual time. Do not double up on doses.

Overdose and Side Effects

Overdose Symptoms: Taking too much Zopiclone can lead to serious consequences, including:

• Severe drowsiness, confusion, or falling into a coma.
• Dizziness or fainting due to low blood pressure.
• Muscle weakness.
• Loss of balance or coordination.
• Shallow or difficult breathing.

Common Side Effects:

• A bitter or metallic taste or dry mouth.
• Daytime drowsiness or fatigue.

Serious Side Effects (rare):

• Memory issues (amnesia).
• Hallucinations or delusions.
• Depression.
• Increased risk of falls, particularly in those over 65.

Allergic Reactions: In rare cases, Zopiclone can cause a severe allergic reaction (anaphylaxis).

Zopiclone During Pregnancy and Breastfeeding

Zopiclone is generally not recommended during pregnancy due to limited information on its safety. If taken towards the end of pregnancy, it may cause drowsiness or withdrawal symptoms in newborns, who might need additional monitoring.

While Zopiclone can pass into breast milk in small amounts, it is usually considered safe for short-term use during breastfeeding. However, avoid sharing a bed with your baby while taking the medication. If your baby appears unusually sleepy or is not feeding well, consult your healthcare provider immediately.

Impact on Fertility

Currently, there is no evidence to suggest that Zopiclone affects fertility in men or women. However, if you are trying to conceive, it’s a good idea to discuss your treatment options with your doctor.

Interactions with Other Medications

Zopiclone can interact with certain medications, potentially increasing side effects. These include drugs used for mental health conditions, epilepsy, allergies, and pain management. Always consult your doctor or pharmacist before starting Zopiclone if you are taking other medications.

Herbal Remedies: Avoid taking herbal supplements that cause drowsiness while using Zopiclone, as this can enhance its sedative effects.